COPD Pathogenesis


Inflammation is present in the lungs, especially the small airway routes, of all people who smoke. COPD Pathogenesis is typical defensive reaction to the inhaled toxins is enhanced in COPD, leading to tissue destruction ,debilitation of the defence mechanisms and interruption of the repair mechanisms. In general, the inflammatory and structural changes in the airway routes increased with disease seriousness and hold on even after smoking cessation. Other than inflammation, two different procedures are associated with the pathogenesis of COPD an irregularity amongst  proteases  and  antiproteases  and an imbalance amongst  oxidants and antioxidants agents in the lungs. Pulmonary Conferences expresses various developing treatments for COPD.


  • Inflammatory mediators
  • Oxidative stress
  • Mucous Hypersecretion
  • Air trapping
  • Airway inflammation
  • Mucociliary dysfunction
  • Protease imbalance
  • Antiprotease imbalance

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